Budd chiari syndrome

Budd chiari syndrome is caused by occlusion of the hepatic veins. One out of every one million people gets the budd chiari syndrome. The budd chiari syndrome is more common in females. The thromboses of the hepatic veins are some examples of the budd chiari syndrome. Hepatic vein obstruction prevents the passage of the blood from flowing out of the liver and then back to the heart. Obstruction of this hepatic vein can be caused by a tumor on the vessel, or ven  a clot in the vessel (hepatic vein thrombosis).

The syndrome can either be acute, chronic, or asymptomatic. Abdominal pain, ascites and hepatomgaly are some of the symptoms of the budd chiari syndrome. The disease budd chiari syndrome is a rare condition induced by thrombotic or nonthrombotic obstruction to the outflow of hepatic venous. Budd is the first person to have described it in 1845, and Chiari is thought to have added the first pathologic description of a liver with “obliterating endophlebitis of the hepatic veins” and this was in 1899. The budd chiari syndrome occurs mostly in patients with underlying thrombotic diathesis which includes myeloproliferative disorders, such as polycythemia vera and paroxysmal nocturnal hemoglobinuria, chronic inflammatory diseases, pregnancy, tumors, clotting disorders and several other infections. The budd chiari syndrome has several symptoms like abdominal swelling or stretching, Pain in the right upper abdomen, vomiting of blood and jaundice or the yellowing of the skin.

The budd chiari syndrome is caused by conditions that make blood clots more likely, including abnormal growth of cells in the bone marrow (myeloproliferative disorders), Inherited (hereditary) or acquired problems with blood clotting, Chronic inflammatory or autoimmune diseases, cancer, types of infections, pregnancy etc. The most common cause of budd chiari syndrome is Hepatic vein obstruction. One of the life-threatening ill effects of the budd chiari syndrome is that it can lead to the failure of the liver. Treatment for this disease varies from one person to the other and greatly depends on the cause of the blockage. Administering Blood-thinning (anticoagulation) medications is one way to treat this disease. Another way is Clot-busting drugs (thrombolytic treatment), and also Treatment for the liver disease, including ascites. Transjugular intrahepatic portosystemic shunt (TIPS), Angioplasty and stent placement and Venous shunt surgery are some of the surgical treatments.